Date

September 2010

Document Type

Thesis

Degree Name

M.P.H.

Department

Dept. of Public Health and Preventive Medicine

Institution

Oregon Health & Science University

Abstract

Objectives: (1) Identify variables associated with retention in an opioid treatment program and (2) investigate the association between continued stimulant use and patient retention. Methods: Patients (n = 153) in an opioid treatment program were enrolled in a clinical trial that randomized participants to six months of buprenorphine /naltrexone or methadone and assessed the measures of liver functioning. A secondary analysis of clinical data assessed patient and program influences on study retention. A Markov chain analysis compared methadone and buprenorphine study participants on the probability of positive urine drug screens for stimulant use. Results: Superior retention time was found in patients on methadone, who began treatment halfway through the study, attended group meetings weekly, had longer periods of time without drug use in the last year, and who were not intravenous users. Buprenorphine was not found to be more effective at decreasing stimulant use than methadone. Co

Identifier

doi:10.6083/M49C6VCZ

School

School of Medicine

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