Dept. of Public Health and Preventive Medicine
Oregon Health & Science University
Background: The survival patterns of patients with pancreatic adenocarcinoma appear to vary between geographical regions and among people of color. A few studies have reported that variations in adequate lymph node assessment (ALNA) across regions have led to poorer survival for several cancers including pancreatic cancer. To date, no study has systematically investigated the variation in the extent of lymph node dissection and impact on overall survival by race and geographic regions in patients with pancreatic adenocarcinoma. Methods: Using the SEER 9 registry database, we selected 3106 patients who had undergone surgical resection for pancreatic adenocarcinoma between 1988 and 2005. We assessed whether the absolute number of lymph nodes resected and the ratio of positive lymph nodes to resected lymph nodes (LNR) differed by race, or geographic regions. In addition, a Cox proportional hazards model was used to estimate hazard ratio (HR) and compare overall survival. Results: In the e
School of Medicine
Patil, Meena, "Impact of regional and racial variation in extent of lymph node dissection on survival in pancreatic adenocarcinoma : a SEER database analysis" (2009). Scholar Archive. 576.