December 2012

Document Type


Degree Name



Dept. of Biomedical Engineering


Oregon Health & Science University


Patients with multiple sclerosis often complain about reduced balance and have increased sway during quiet standing. However, thus far, no investigations have been conducted to identify the altered balance strategies used by these subjects while standing upright. Recently, young healthy adults were found to use an inverted pendulum-like, ankle strategy during quiet standing below 1Hz and a double inverted pendulum-like hip strategy above 1Hz. Here we present evidence for a difference in balance strategies used by subjects with MS compared to control subjects, using coherence and cophase analysis of trunk and leg segment accelerometry and kinematics. A high coherence together with a low cophase relationship was defined as ankle strategy, whereas a high coherence together with a 180 degrees cophase was defined as hip strategy. Thirty-seven subjects with MS and 20 healthy age-matched control subjects stood quietly for 30 seconds for 3 trials in each of two conditions: eyes open and eyes c




School of Medicine



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