British Medical Journal, 1888, v.2, pp. 1321-6
Important experiemental work on cardiac overstrain was carried out by Roy and Adami who considered that mechanical overstrain caused chronic thickening of the cardiac valves.
Morton no.: 2793
Roy, Charles Smart and Adami, John George, "Remarks on failure of the heart from overstain." (1888). Classic Article Collection. 93.